Easter Seals Jobs

Reference #: 1013894 SHIFT:Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP's Commitment to Diversity, Equity, and Inclusion

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

A Brief Overview Dr Tasian's translational laboratory in the Division of Oncology and Center for Childhood Cancer Research focuses upon the development of new treatments for high-risk childhood leukemias with an emphasis upon small molecule inhibitor therapies and cellular (CAR T cell) immunotherapies. Dr Tasian is seeking a motivated, dynamic, and hard-working candidate to join her laboratory to assist with preclinical animal model studies and with correlative biology studies for childhood leukemia clinical trials using primary patient samples. A minimum commitment of 2 years is required for this position.

A successful applicant must be a highly collaborative, collegial team player with an ability to work well with others in a translational laboratory setting and with good instincts and experimental troubleshooting skills. They will be supervised in part by a senior PhD scientist/laboratory manager and work closely with PhD- or MD-trained post-doctoral fellows and other BA/BS-trained research technicians.

What you will do Process patient leukemia specimens following appropriate training, handle confidential patient-related materials, and maintain a protected database of confidential patient-related information from clinical trials. Perform specialized animal studies (immunocompromised mice) for human leukemia xenotransplantation, preclinical drug or cell therapy treatment, disease monitoring, treatment efficacy analyses, and pharmacodynamic monitoring. Specific animal skills will be mastered after training and include retro-orbital venous bleeding, tail vein injections, intraperitoneal injections, oral gavage, bioluminescent imaging, animal sacrifice, and organ harvesting and tissue processing. Learn specialized flow cytometry analysis of mouse and human samples and to use flow cytometry data analysis and graphing software. Troubleshoot and plan experiments with appropriate Principal Investigator and post-doctoral fellow oversight. Ideally, the candidate will contribute to writing of scientific manuscripts and to figure preparation; co-authorship will be commensurate with level of project involvement and manuscript contributions. Handle multiple, time-dependent tasks efficiently and conscientiously and to conduct oneself with professionalism and maturity. Being a good team player is a must for our laboratory culture, and a good sense of humor is also quite welcome! 5. Excellent organizational and analytical skills. 6. Ability to use computers, email, Word, and PowerPoint software and to learn other programs needed for data presentation and figure preparation (eg, Prism).

Education Qualifications High School Diploma / GED Required Associate's Degree Preferred Bachelor's Degree in a scientific discipline Preferred

Experience Qualifications At least one (1) year of related classroom experience or successful completion of technical training program (eg. Wistar, WPSI) and research laboratory experience Required At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred

Skills and Abilities Intermediate understanding of lab procedures, protocols, and equipment. Ability to use computers, email, Word, and PowerPoint software and to learn other programs needed for data presentation and figure preparation (eg, Prism Basic exposure to lab specific experiments / techniques and scientific analysis Excellent verbal and written communications skills Excellent organizational and analytical skills Solid critical thinking / problem-solving skills Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine. Learn more.

Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

EEO / VEVRAA Federal Contractor |  Tobacco Statement

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.