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Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Job Description

2025 Chromatography Method Development Intern Overview

Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.

The Drug Metabolite Screening Intern will support the Drug Metabolism and Disposition group in building and optimizing methods on high-end LC-MS systems to maximize the pipeline impact of our assays. The intern will modernize our current high-throughput metabolite ID LC-MS/MS workflows to improve separation of drug metabolites in liver microsomes, liver S9, and in vivo PK samples while reducing gradient length and increasing robustness across days of injection time. They will also evaluate control compounds and assay parameters to determine whether they are adequate for current usage. The end result should be improved LC-MS/MS methods enabling metabolite soft-spot analysis across multiple therapeutic areas in the AbbVie discovery pipeline.

This position will be based in North Chicago, IL.

Key responsibilities include:

• Evaluate current LC methods and protocols and identify key parameters to optimize, with a focus on column chemistry, solvents, and gradient length.

• Develop robust LC methods with improved, consistent separation and test across a broad range of chemical space using commercial and internal compounds in relevant complex matrices.

• If multiple methods are required, define appropriate conditions to use each method (chemical space, number of metabolites, ionization polarity, etc.)

• Compile historic control data and propose QC cutoffs consistent with data utilization.

• Present results to department and present at internal poster session.

Qualifications

Minimum Qualifications

• Currently enrolled in university, pursuing a Master’s or PhD in Chemistry, Biochemistry, Chemical Biology, or related field.

• Must be enrolled in university for at least one semester following the internship.

• Experience in liquid chromatography separations and/or analysis by mass spectrometry.

• Track record of performing independent scientific research.

• Strong written and verbal communication skills.

Preferred Qualifications

• Expected graduation date between December 2025 - June 2026.

• Experience in liquid chromatography method development strongly preferred.

• Exposure to Thermo Orbitrap and ABSciex ToF mass spectrometers.

• Exposure to drug metabolite identification (enzymes, biotransformation pathways, structural elucidation).

Benefits and Amenities

• Competitive pay.

• Relocation support for eligible students.

• Select wellness benefits and paid holiday / sick time.

Equal Employment Opportunity

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

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AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Salary: $58,656 - $98,000