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New Jersey's academic health center, Rutgers Biomedical and Health Sciences (RBHS) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University-New Brunswick and collaborating university wide, RBHS includes eight schools, a behavioral health network, and five centers and institutes that focus on cancer treatment and research, neuroscience, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research.Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers.Our clinical and academic facilities are located throughout the state-at Rutgers University-New Brunswick, including Piscataway; and at locations in Newark, Scotch Plains, Somerset, Stratford, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, Newark's University Hospital in Newark, and other affiliates.Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives.

Rutgers, The State University of New Jersey, is seeking a Temporary Research Assistant for NJMS- Microbiology, Biochemistry & Molecular genetics. The Temporary Research Assistant will pursue efforts at developing an assay to identify small molecule blockers of protein biosynthesis in microbes for the development of new antibacterial drug treatments. The assay measurees the physical assembly of the complex between Ef- Tu and tRNA, the key components of the ribosomal translation machinery in the microbes, in a GTP- dependent manner.Among the key duties of the following:

Rutgers offers a comprehensive benefit program to eligible employees. For details, please go to http://uhr.rutgers.edu/benefits/benefits-overview.

1. Protein and tRNA purification and analysis and for preparations for HTS
2. Protein and nucleic acid expression and purification, expression in a bacterial system, chromatographic separations, protein and nucleic acid labeling, and fluorescence methods
3. Performing protein biosynthesis and in vitro translation assays
4. Conjugation of fluorescent dyes to the components of the ribosomal translation system and characterization of the conjugates by fluorescence spectroscopy
5. Understands and adheres to Rutgers' compliance standards as they appear in RBHS's Corporate Compliance Policy, Code of Conduct and Conflict of Interest Policy.
6. Performs other related duties as assigned.
7. Keeps abreast of all pertinent federal, state and Rutgers' regulations, laws and policies as they presently exist and as they change or are modified.

1) Protein and nucleic acid expression and purification. Expression in bacterial systems, and chromatographic separation using FPLC and HPLC.
2) Protein biosynthesis and in vitro translation. Experience with tRNAs biochemistry. Protein structure and function.
3) Fluorescence methods. Conjugation of fluorescent dyes to proteins and nucleic acids. Characterization of fluorescent reagents by fluorescence spectroscopy. fluorescence resonance energy transfer (FRET).
4) Molecular biology. DNA cloning and mutagenesis, restriction analysis, DNA sequencing, PCR, bacterial fermentation.
5) Structure-function relationship in proteins and nucleic acids.
6) Experience with high-throughput (HTS) screening is helpful.
7) Effective oral and written communication skills. Ability to publish scientific research papers/articles and reports. Must be computer literate with proficiency and working knowledge of Microsoft Word, Excel and PowerPoint.