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Job Description

Postdoctoral Fellow in Computational Chemistry

Organization: Schlessinger Lab - Structural Bioinformatics and Computational Chemistry Location: Icahn School of Medicine at Mount Sinai, New York, NY Website: schlessingerlab.org

Background:

The Schlessinger Lab at the Icahn School of Medicine at Mount Sinai in New York is seeking a highly motivated Postdoctoral Researcher to join our team in the field of computational chemistry and membrane physiology. Our lab focuses on developing and applying advanced computational methods to unravel the molecular mechanisms of proteins and drugs, with the ultimate goal of advancing next-generation therapeutics. We currently have an NIH-funded project centered around studying the structure, function, and drug discovery of membrane transporters.

Position Overview:

We are looking for a recent PhD graduate with a strong background in membrane protein structural biology and computational chemistry to contribute to our collaborative projects as part of an interdisciplinary team. The ideal candidate should possess excellent analytical skills, be able to work independently, and have experience leading projects to successful completion.

Specific Responsibilities:

The successful candidate will be responsible for applying various computational methods to design tool compounds for biomedically important proteins, with a focus on membrane proteins.

Qualifications

How to Apply:

Interested applicants should email the following documents to Dr. Avner Schlessinger (avner.schlessinger[at]mssm.edu):

? CV

? Brief description of research interests and experience

? List of 3 references

Responsibilities

Position Requirements:

• PhD in Biophysics, biochemistry, chemistry, physics, computer science, or related field.

• Significant experience and knowledge of computational structural biology, including expertise in structural modeling, molecular docking, or sequence analysis methods.

• Keen interest in applying quantitative approaches, such as computer-aided drug design, to address biological problems in collaboration with experimental biologists.

• Strong research background and a track record of publications in characterization of protein/ligand interactions, as well as experience using molecular docking and structural modeling.

• Proven expertise in analyzing membrane proteins using computational and experimental approaches .

• Highly motivated and creative candidates with a strong publication record are strongly encouraged to apply.

About Us

Strength Through Diversity

The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:

• Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential.

• Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination.

• Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.

At Mount Sinai, our leaders strive to learn, empower others, and embrace change to further advance equity and improve the well-being of staff, patients, and the organization. We expect our leaders to embrace anti-racism, create a collaborative and respectful environment, and constructively disrupt the status quo to improve the system and enhance care for our patients. We work hard to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to advance professionally.

Explore more about this opportunity and how you can help us write a new chapter in our history!

“About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism.”

EOE Minorities/Women/Disabled/Veterans

Compensation Statement

Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.