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Apply for Job Job ID366023 LocationTwin Cities Job FamilyResearch Full/Part TimeFull-Time Regular/TemporaryRegular Job Code8351RL Employee ClassCivil Service Add to Favorite Jobs Email this Job About the Job This position will study targeted therapy for breast cancer growth and metastasis. Ongoing research projects in the laboratory include the study of growth factor signaling in regulating growth and metastasis of breast cancer, use of animal models to study the effect of signaling inhibitors and natural killer cell based drugs on biology and metastasis of breast cancer and in vivo imaging to monitor response to targeted therapies. Specific responsibilities/duties include: Research - 60%: Conduct research under the PI's direction; perform supervised scientific experiments and professional laboratory work on growth factor receptor signaling and targeting in breast cancer. The work will involve analyzing signaling pathways using cell culture, western blotting; analyzing cells and tissues using flow cytometry; analyses using real-time PCR; daily record keeping; analyses of data; write up results and present them in lab meetings; read scientific literature based on the projects. The employee will plan experiments in collaboration with the supervisor and will be expected to independently problem solve and implement changes necessary to ensure success of the work. Mouse work - 20%: Assisting/performing monitoring of mice, injecting and implanting tumor cells in mice, measuring tumor growth and imaging athymic mice during experiments, weighing mice and administering treatments to mice, harvesting and processing of blood, tumors, and lungs of mice and analysis of metastases. Lab administration and maintenance - 15%: General lab maintenance including lab equipment, ordering laboratory chemicals and supplies, making solutions, hazardous waste management, stocking of lab & tissue culture, routine lab upkeep; preparing research summaries. Orient and Train - 5%: Assist in the training of incoming lab members, including undergraduate students and maintain lab safety and training records. Qualifications All required qualifications must be documented on application materials. Required: * Bachelor's degree in biology, biochemistry, or a related discipline and work experience related to the job to equal four years. * Experience with cell culture of cell lines. The selected candidate will have interest in animal models of cancer biology and use of modern molecular biology techniques. They will also be expected to demonstrate reliability, attention to detail, motivation, ability to follow protocols, work independently, and multi-task. Preferred: * Experience and demonstrated technical ability in biochemical and analytical assays. * Western blotting, isolation of RNA and PCR, and flow cytometry. * Strong verbal and written communication skills. * Experience with mouse handling. * Ability to read and evaluate scientific papers; ability to write up scientific results and contribute to editing manuscripts; strong computer and organizational skills. About the Department The Masonic Cancer Center (MCC) is an NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of Minnesota and the surrounding region. Since the time of the first award in 1997, there has been consistent growth of the membership and research base, enabling our center to further advance our knowledge and enhance care for our catchment area. We are driven to be the choice academic healthcare environment for patients, clinicians, scientists and students who seek exceptional, compassionate, precision cancer therapy; innovative clinical trials and prevention programs; cutting-edge research opportunities; and outstanding advanced education. Pay and Benefits Pay Range: $41,600 - $43,000; depending on education/qualifications/experience Time Appointment: 75%-100% Appointment Position Type:Civil-Service & Non-Faculty Labor Represen ed Staff Please visit the Office of Human Resources website for more information regarding benefit eligibility. The University offers a comprehensive benefits package that includes: Competitive wages, paid holidays, and generous time off Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program Low-cost medical, dental, and pharmacy plans Healthcare and dependent care flexible spending accounts University HSA contributions Disability and employer-paid life insurance Employee wellbeing program Excellent retirement plans with employer contribution Public Service Loan Forgiveness (PSLF) opportunity Financial counseling services Employee Assistance Program with eight sessions of counseling at no cost Employee Transit Pass with free or reduced rates in the Twin Cities metro area How To Apply Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume. Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section. To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647. Diversity Employment Requirements Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment. About the U of M The University of Minnesota, Twin Cities (UMTC) The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations. At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022). The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.