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Apply for Job Job ID362273 LocationAll Other -See Job Description Job FamilyAcademic Full/Part TimeFull-Time Regular/TemporaryRegular Job Code9546 Employee ClassAcad Prof and Admin Add to Favorite Jobs Email this Job About the Job The Aslanidi Lab research is focused on bioengineering and the application of Adeno-Associated virus (AAV) vectors for the purpose of lung-directed gene. The research addresses several important drawbacks in AAV-based gene therapy such as vector efficiency to transduce lung epithelial and basal cells, pre-existing and therapy-activated immunogenicity, scaled-up vector production, and assessment of efficacy in pre-clinical animal models. The goal of our research is to ensure advancement of gene therapy treatment for patients with lung-specific genetic diseases. Position Duties and Responsibilities Conduct research in a self-sufficient and self-motivated manner. Conduct experiments on novel viral vector design, development, and validation. Development of a novel protocol to improve viral vector production. Conduct experiments on immune responses toward viral capsid and encoded transgene. Work with airway epithelial primary cells, and blood from small and large animals, as well as humans. Carry out animal experiments, necropsy, and tissue processing. Evaluate AAV-mediated gene expression in airway epithelial cell by qPCR, immunostaining and flow cytometry. Collect and analyze data to support the research claims. Write reports, and manuscripts and give scientific presentations. Comply with IBC, IACUC, and IRB policies, and maintain a safe and healthy laboratory environment. Focus of Job Responsibilities 70% - Ongoing Research Design and implementation of hypothesis-driven research projects. 15% - Analysis & Review Analysis and review of generated data and reviewing previously reported scientific literature. 15% - Scientific writing and presentation The Research and Innovation Office (RIO) and The Hormel Institute endorses a "work with flexibility" approach that offers a welcoming and flexible work environment where everyone is inspired to do their best. Work location options include working fully remote, partially remote, or entirely in the office and are based on the work of the position. Some on-site work may be necessary for certain positions, even those designated as fully remote. Because we are a land-grant institution that serves the state, the University will continue to- in most cases- expect employees to live in Minnesota. This position has been designated as eligible for Flexible Work Profile One. Flexible Work Profile One is expected to work primarily on-site. Your office will be located at The Hormel Institute in Austin, MN. The Hormel Institute management retains the right to modify flexible work arrangement agreements on a temporary or permanent basis for any reason at any time. Qualifications Required Qualifications Ph.D., DVM, MD or equivalent. Preferred Qualifications Candidates with experience in gene therapy and viral vectors, particularly Adeno-associated virus vectors. Candidates with robust expertise in molecular biology and bioprocessing. Candidate with experience in primary airway epithelial cell biology. Candidates interested in pre-clinical and translational research. Candidates demonstrated evidence of relevant training and peer-reviewed publications. About the Department The Hormel Institute is an independent biomedical research institution within the University of Minnesota's Research and Innovation Office. Established in 1942, our mission is to conduct research and provide education in the biological sciences with applications in medicine and agriculture, specifically by understanding, treating, and controlling cancer and other chronic diseases. The Hormel Institute serves as a center of technical and educational expertise for the benefit of the local community, the State of Minnesota, and beyond. We are located in the uniquely diverse rural community of Austin, MN, conveni ntly only 35 miles from Rochester, MN, and 100 miles (1.5 hours) south of Minneapolis/St. Paul. The Hormel Institute is committed to fostering a work environment that promotes inclusive excellence, supportive employee practices, and encourages diversity of thought that drives innovation and creativity in our science. Benefits Working at the University At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work. The University also offers a comprehensive benefits package that includes: Competitive wages, paid holidays, and generous time off Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program Low-cost medical, dental, and pharmacy plans Healthcare and dependent care flexible spending accounts University HSA contributions Disability and employer-paid life insurance Employee wellbeing program Excellent retirement plans with employer contribution Public Service Loan Forgiveness (PSLF) opportunity Financial counseling services Employee Assistance Program with eight sessions of counseling at no cost Please visit the Office of Human Resources website for more information regarding benefits. How To Apply Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume. Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section. To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647. Diversity Employment Requirements Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment. About the U of M The University of Minnesota, Twin Cities (UMTC) The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations. At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity... For full info follow application link. The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.