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Research Associate - Hard X-ray Spectroscopy

Job ID

6132

Location

SLAC - Menlo Park, CA

Full-Time

Temporary

SLAC Job Postings

Position overview:

The Stanford Synchrotron Radiation Lightsource (SSRL), a Directorate of the SLAC National Accelerator Laboratory, Stanford University, seeks a Research Associate with a strong background in the application of protein purification, crystal growth, X-ray crystallography, X-ray absorption spectroscopy and EXAFS methods to metalloenzyme systems to work in a diverse team of scientists developing and delivering high-throughput automation tools for drug discovery. This project is part of DOE-BES¿s BRaVE aware designed to leverage DOE¿s distinctive national laboratory capabilities to support U.S. preparedness and response to future potential biological crises.

In this position, you will work within the Structural Molecular Biology group at SSRL and work closely with the staff scientists and engineers across divisions to focus on interfacing beamline automation in hard X-ray spectroscopy with solution and crystal sample. measurements. You will have the opportunity to participate in projects relevant to biological metalloenzyme catalysis, working closely with SSRL staff members and the BRaVE collaborators involved in metalloenzyme structure function correlations. You will have the opportunity to publish joint-author manuscripts.

Your specific responsibilities include:

• Work collaboratively with BRaVE scientists performing biological X-ray measurements to understand drug-metalloenzyme interactions and to contribute to the development of new drugs.

• Write proposals to obtain beamtime at SSRL and assist in data-collection on biological systems relevant to human diseases and pathogenesis.

• Work closely with BRaVE engineers to develop high-throughput pipeline for XAS and EXAFS measurements.

• Work closely with BRaVE AI experts to help develop a pipeline for XANES to Fourier transform mapping.

Note: The Research Associate role is a fixed term staff position. This is a 1-year fixed term position with the possibility of extension. Assignment duration is contingent upon project needs and funding.

Applicants must provide evidence of a PhD degree. Applicants should also include a cover letter, a statement of research area including brief summary of accomplishments and a curriculum vitae. Supplying letters of recommendation or names to contact for reference with the application is also useful.

SLAC is a U.S. Department of Energy (DOE) laboratory operated by Stanford University and based in Menlo Park, CA. Given the nature of this position, SLAC will require onsite work.

To be successful in this position you will bring:

• PhD in biology or structural biology with demonstrated coursework or research experience in coupling synchrotron-based X-ray spectroscopy and crystallography applications in biology research.

• Demonstrated experience in protein purification, crystallization and measurement at synchrotron sources.

• Demonstrated research experience as evidenced by a publication record.

• Willingness to learn any knowledge/experience gaps.

• Demonstrated effective written and verbal communications skills and ability to work/communicate effectively with a diverse biology research community.

• Demonstrated ability to work independently and in a multidisciplinary team environment.

• Motivation to form strong multi-institute collaborations.

SLAC employee competencies:

• Effective Decisions: Uses job knowledge and solid judgment to make quality decisions in a timely manner.

• Self-Development: Pursues a variety of venues and opportunities to continue learning and developing.

• Dependability: Can be counted on to deliver results with a sense of personal responsibility for expected outcomes.

• Initiative: Pursues work and interactions proactively with optimism, positive energy, and motivation to move things forward.

• Adaptability: Flexes as needed when change occurs, maintains an open outlook while adjusting and accommodating changes.

• Communication: Ensures effective information flow to various audiences and creates and delivers clear, appropriate written, spoken, presented messages.

• Relationships: Builds relationships to foster trust, collaboration, and a positive climate to achieve common goals.

Physical requirements and Working conditions:

• Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Work standards:

• Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.

• Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for environment, safety and security; communicates related concerns; uses and promotes safe behaviors based on training and lessons learned.Meets the applicable roles and responsibilities as described in the ESH Manual, Chapter 1¿General Policy and Responsibilities: http://www-group.slac.stanford.edu/esh/eshmanual/pdfs/ESHch01.pdf

• Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu/

• Classification Title: Research Assoc-Experimental

• Grade: G, Job code: 0127

• Employment Duration: Fixed term ¿ 1 year

The expected pay range for this position is $70,000 - $100,000 per annum. SLAC National Accelerator Laboratory/Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.

SLAC National Accelerator Laboratory is an Affirmative Action / Equal Opportunity Employer and supports diversity in the workplace. All employment decisions are made without regard to race, color, religion, sex, national origin, age, disability, veteran status, marital or family status, sexual orientation, gender identity, or genetic information. All staff at SLAC National Accelerator Laboratory must be able to demonstrate the legal right to work in the United States. SLAC is an E-Verify employer.