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NATIONAL LEADERS IN PEDIATRIC CARE

Ranked among the top 10 pediatric hospitals in the nation, Children’s Hospital Los Angeles (CHLA) provides the best care for kids in California.

Here world-class experts in medicine, education and research work together to deliver family-centered care half a million times each year. From primary to complex critical care, more than 350 programs and services are offered, each one specially designed for children.

The CHLA of the future is brighter than can be imagined. Investments in technology, research and innovation will create care that is personal, convenient and empowering. Our scientists will work with clinical experts to take laboratory discoveries and create treatments that are a perfect match for every patient. And together, CHLA team members will turn health care into health transformation.

Join a hospital where the work you do will matter—to you, to your colleagues, and above all, to our patients and families. The work will be challenging, but always rewarding.

It’s Work That Matters.

Overview

Purpose Statement/Position Summary: The CHLA INSPIRE (Innovative Synergistic Pediatric Infection Research) laboratory group focuses on optimizing antibiotic therapies, especially for difficult to treat pathogens. Within INSPIRE, Drs. Neely and Gibson direct laboratories that primarily use the hollow fiber infection model (HFIM) to mimic human pharmacokinetics and pharmacodynamics (PK-PD) in vitro to improve dosing strategies and select ideal combination therapies for pathogens. They use sophisticated mathematical and statistical models to interpret the data from the HFIM, mostly using R. Currently, they study bacterial pathogens (including non-tuberculous mycobacteria, Staph. aureus, Pseudomonas, Acinetobacter, Burkholderia cepacia) and viruses (CMV). The primary objective of this role is to oversee other members of Dr. Neely’s and Gibson’s laboratories in the design and completion of experiments. Scientific work will be with the HFIM, as well as completing other microbiologic studies.

Reporting to the directors, the Research Scientist will: 1) Develop, validate, and implement new or modified lab-developed methods, including the HFIM; 2) Oversee and coordinate daily work of other lab members; 3) For those with interest or skills in PK-PD modeling, contribute to development, refinement, and use of digital models fitted to experimental data; 4). Contribute to the preparation, development, and publication of research findings in peer-reviewed journals. Additionally, the Research Scientist may be expected to present their work at professional meetings when appropriate.

Minimum Qualifications/Work Experience: 2+ years of post-graduate research experience with independently planning and implementing experiments. The candidate should also have experience with mentoring and assisting other lab members. Microbiologic techniques (bacterial culture, CFU assays, MICs) and Planning experiments. Experience with mammalian cell culture, PCR, microscopy, and with supervising and assisting other lab members experience is highly preferred. Prior experience with the hollow fiber system is a bonus, but not required, as we will train the successful candidate as needed. Similarly, prior PK-PD modeling experience and/or high comfort level with R are desirable but not required skills. Candidates must have expertise in basic bacterial culture and quantification techniques. Candidates who have prior HFIM experience and/or PK-PD data modeling experience will have a competitive advantage for this position, but such experience is not required.

Education/Licensure/Certification: PhD or equivalent advanced degree with 2+ years of relevant experiences or Master’s Degree with 5+ years of relevant experiences.

Pay Scale Information

$64,688.00-$116,563.00

CHLA values the contribution each Team Member brings to our organization. Final determination of a successful candidate’s starting pay will vary based on a number of factors, including, but not limited to education and experience within the job or the industry. The pay scale listed for this position is generally for candidates that meet the specified qualifications and requirements listed on this specific job description. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. We provide a competitive compensation package that recognizes your experience, credentials, and education alongside a robust benefits program to meet your needs. CHLA looks forward to introducing you to our world-class organization where we create hope and build healthier futures.

Children's Hospital Los Angeles (CHLA) is a leader in pediatric and adolescent health both here and across the globe. As a premier Magnet teaching hospital, you’ll find an environment that’s alive with learning, rooted in care and compassion, and home to thought leadership and unwavering support. CHLA is dedicated to creating hope and building healthier futures – for our patients, as well as for you and your career!

CHLA has been affiliated with the Keck School of Medicine of the University of Southern California since 1932.

At Children’s Hospital Los Angeles, our work matters. And so do each and every one of our valued team members. CHLA is an Equal Employment Opportunity employer. We consider qualified applicants for all positions without regard to race, color, religion, creed, national origin, sex, gender identity, age, physical or mental disability, sexual orientation, marital status, veteran or military status, genetic information or any other legally protected basis under federal, state or local laws, regulations or ordinances. We will also consider for employment qualified applicants with criminal history, in a manner consistent with the requirements of state and local laws, including the LA City Fair Chance Ordinance and SF Fair Chance Ordinance.

Qualified Applicants with disabilities are entitled to reasonable accommodation under the California Fair Employment and Housing Act and the Americans with Disabilities Act. Please contact CHLA Human Resources if you need assistance completing the application process.

Diversity inspires innovation. Our experiences, perspectives and backgrounds allow us to better serve our patients and create a strong community at CHLA.

Infectious Diseases - Research