Job Information
Pennsylvania State University Postdoctoral Scholar - Pharmacology in Hershey, Pennsylvania
APPLICATION INSTRUCTIONS:
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CURRENT PENN STATE STUDENT (not employed previously at the university) and seeking employment with Penn State, please login to Workday to complete the student application process. (https://pennstateoffice365.sharepoint.com/:b:/s/KnowledgeBaseArticlesSharing/Eeys15Xva4hFokHVtbP1eGIB5i1WFLc-J3k9KHgrFYZ7mg) Please do not apply here, apply internally through Workday.
If you are NOT a current employee or student, please click “Apply” and complete the application process for external applicants (https://hr.psu.edu/sites/hr/files/Application_Process_for_External_Applications_Non-Penn_State_Employees_.pdf) .
JOB DESCRIPTION AND POSITION REQUIREMENTS:
The Penn State College of Medicine, Department of Pharmacology, in Hershey, PA, is seeking a highly motivated Postdoctoral Scholar to join our translational molecular biology group focused on Amyotrophic Lateral Sclerosis (ALS) research. The successful candidate will work closely with a multidisciplinary team to advance our understanding of ALS molecular etiology and develop potential new disease biomarker assays. The responsibilities will encompass leading or contributing to various ALS experiments, including biophysical protein assays, cell assays, and assays using human samples. Additionally, the successful candidate oversees the organization of a biobank housing human samples, ensuring meticulous documentation and adherence to ethical and regulatory standards.
The successful candidate will assist with Institutional Review Board (IRB) processes and collaborate with regulatory authorities to ensure compliance. As a valued team member, the successful candidate contributes to data analysis, manuscript preparation, and collaborative discussions, fostering a dynamic research environment.
The ideal candidate holds a Ph.D. in Molecular Biology, Biochemistry, Neuroscience, or related fields, possesses strong molecular biology expertise, and ideally has experience in protein misfolding and/or amyloid research. Strong knowledge of protein biochemistry with extensive hands-on experience in protein expression and purification in yeast, bacterial, and mammalian cell lines. Experience in tissue culture and cell line maintenance, transfection optimization, plasmid transfection, cell viability assays of neuron-like cells, and working experience with molecular biology techniques including transformation, plasmid extraction, cloning techniques, site-directed mutagenesis, Primer design, PCR, DNA sequence analysis.
The successful candidate will interact with other scientists in the lab and participate in lab life by offering training and mentoring other members. Effective communication, organizational skills, and a commitment to advancing ALS knowledge are essential. Join us in our mission to make strides in ALS research and translate scientific discoveries into tangible benefits for patients.
Suggested Technique Experience:
PCR/ primer design, site-directed mutagenesis, DNA sequence analysis, and bacterial cloning
Protein expression and purification, utilizing affinity chromatography and size exclusion chromatography on an AKTA Pure FPLC machine.
Exosome isolation using ultracentrifugation is a plus
ELISA, Western blotting, and other immunoassays
Mammalian cell culture including human iPSC culture
Organization and accurate pipetting
This is a limited-term appointment funded for one year from date of hire.
Employment will require successful completion of background check(s) in accordance with University polices.
The Pennsylvania State University is committed to and accountable for advancing diversity, equity, and inclusion in all of its forms. We embrace individual uniqueness, foster a culture of inclusive excellence that supports both broad and specific diversity initiatives, leverage the educational and institutional benefits of diversity, and engage all individuals to help them thrive. We value inclusive excellence as a core strength and an essential element of our public service mission.
CAMPUS SECURITY CRIME STATISTICS:
Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act and the Pennsylvania Act of 1988, Penn State publishes a combined Annual Security and Annual Fire Safety Report (ASR). The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters. The ASR is available for review here (https://police.psu.edu/annual-security-reports) .
Employment with the University will require successful completion of background check(s) in accordance with University policies.
EEO IS THE LAW
Penn State is an equal opportunity, affirmative action employer, and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If you are unable to use our online application process due to an impairment or disability, please contact 814-865-1473.
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