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Children's Hospital Medical Center Staff Scientist (Rubinstein) in Cincinnati, Ohio

Job Description At Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children's. Cincinnati Children's Hospital Has Been Named: * Consistently recognized by U.S. News & World Report as a top 10 children's hospital in the nation * One of four Medical Centers making the list of the 2022 Glassdoor Best Places to Work * A Top Hospital and Health System for Diversity recognized by DiversityInc * One of the nation's most innovative companies by Fortune in March 2023 * An LGBTQ+ Healthcare Equality Top Performer in 2022 by The Human Rights Campaign (HRC) The Human Immune Monitoring Program is a translational research hub that aims to help pre-clinical and clinical investigators working with immune and cellular therapies to plan, run, and interpret correlative studies performed using samples from therapy recipients. The program seeks a research scientist to lead the daily research activities in conjunction with the program leader Dr. Jeremy Rubinstein. The majority of assays will be performed by CCHMC Shared Facilities (core labs). We anticipate that frequently performed assays done in core labs will include flow cytometry, cytokine analysis, ELISpot, DNA and RNA sequencing (bulk and single cell), metabolomics/proteomics, and CAR-T characterization. The job responsibilities will include, but are not limited to: * Meeting with collaborating research teams to help determine appropriate correlative questions and determination of necessary patient sample volumes * Receipt, processing, storage, and collation of research specimens * Performing any necessary preparative steps done on samples prior to handing off to core facilities; this would include things like Ficoll separation, DNA or RNA isolation, antibody staining for flow cytometric analysis, etc * Managing all elements of billing and payment for performed assays * Analysis and interpretation of results * Taking part in the scientific writing process for grant submission and publication * Following the scientific literature to discover and potentially implement new research assays and strategies This position will be the day to day manager of all elements of the program and is suitable for scientists with at least 10 years of experience following their terminal degree JOB RESPONSIBILITIES * Conduct Research/Lab Administration - Plans, directs and executes scientific research and laboratory experiments. Investigates the feasibility of applying a variety of scientific principles and concepts to solve problems. Works on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors, applying broad knowledge of principles, theories and standard scientific/research protocols. Uses professional concepts in accordance with objectives to solve complex problems in creative and effective ways. Exercises judgment within broadly defined practices and policies in selecting methods, techniques and evaluation criteria for obtaining results. Responsible for lab administration (IRB/IACCUC/biosafety). May oversee divisional or institutional core facilities, managing and/or providing training for instrumentation. Research and improve current methods and evaluate innovative techniques. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientifApply here: https://www.aplitrak.com/?adid=YmJnZW5lcmljLjU5MzAzLjEwNTA4QGNpbmNpbm5hdGljaGlsZHJlbnNjb21wLmFwbGl0cmFrLmNvbQ

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