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Position Title:Postdoctoral Research Associate

Appointment Type:Post Doc/Trainee

Job Description:Summary of Duties and Responsibilities:

The Strable Lab in the Department of Genetics, Development and Cell Biology seeks a highly motivated and skilled postdoctoral researcher with training in molecular biology, plant genetics, cell biology, and/or bioinformatics to investigate meristem activity and function related to rice development at single cell/nuclei resolution. This is a 12-month position with annual renewal contingent upon available funding.

In this role, you will design and perform single-cell RNA-sequencing on rice vegetative and reproductive apical meristems utilizing latest and emerging single-cell technologies. You will work to characterize and functionally validate rice cell-type-specific transcriptional programs, their regulation during development, as well as the downstream networks of cell-type-specific transcriptional programs, conduct RNA in situ analyses and carry out developmental genetic analyses of rice carrying mutations in the cytokinin pathway. You will meet weekly with Dr. Strable to discuss experimental design and approaches, data and analyses, best practices in proposal writing, preparation and workshopping manuscripts, mentoring, and career trajectories. You will also be expected to assist training and mentoring undergraduate and graduate students, as well as visiting scientists, and to participate in lab outreach activities that are central to the broader impacts of the research.

Applicants should have a sound understanding of vegetative and reproductive meristems and the ability to stage and dissect them as well as be proficient in single cell transcriptomic data analysis, including, but not limited to implementing CellRanger, Seurat, Monocle and/or Slingshot/tradeSeq packages.

Required Minimum Qualifications:

Ph.D. in molecular biology, genetics, developmental biology, plant biology, integrative biology or bioinformatics or related field

Preferred Qualifications:

• Ph.D. awarded no more than five years prior to the start of the appointment.

• Experience in plant development, especially rice growth and development, functional genomics, evolution, gene expression/regulation and biological networks.

• Demonstrated expertise and hands-on experience in plant molecular biology, plant genetics, and bioinformatics, and in experimental design and analyses of genomics data, including next-generation sequencing analyses, and a strong track record of research productivity and independence in these fields.

• Evidenced skills in protoplast and nuclei isolation, single cell transcriptomic analyses including related informatics packages, trajectory inference analysis and/or data integration.

• Experience with DNA- and RNA- related experimental approaches, RNA in situ hybridization, histology and microscopy, including bright field, confocal laser and scanning electron microscopy.

• Demonstrated ability and skills to communicate effectively verbally and in writing, to work as a team, and to collaborate with other researchers and labs.

Department Website:

https://www.gdcb.iastate.edu/

Proposed Start Date:January 2, 2025

Proposed End Date or Length of Term:December 31, 2025

Number of Months Employed Per Year:12 Month Work Period

Time Type:Full time

Application Instructions:

To apply for this position, please click on “Apply” and complete the Employment Application. Please be prepared to enter or attach the following:1) Resume/Curriculum Vitae2) Letter of Application/Cover LetterIf you have questions regarding this application process, please email employment@iastate.edu or call 515-294-4800 or Toll Free: 1-877-477-7485.Why Choose ISU?Iowa State Postdocs enjoy comprehensive health and work-life benefits, including medical and dental; as well as:• Retirement benefits including defined benefit and defined contribution plans• Generous vacation, holiday, and sick time and leave plans• Onsite childcare (Ames, Iowa)• Flexible Spending Accounts• Various voluntary benefits and discounts• Employee Assistance Program• Wellbeing Program

Original Posting Date: September 16, 2024

Posting Close Date:September 23, 2024

Job Requisition Number:R15527

By focusing on the future and providing the best student experience possible, Iowa State attracts students and faculty who want to make a difference. With a comprehensive land-grant mission of education, research, extension and outreach, we produce scholars whose ideas change the world. And through Innovate at Iowa State , we provide innovative and entrepreneurial opportunities for students of all backgrounds. Located just 30 minutes north of Des Moines, the city of Ames was recently named one of the Top 10 cities in the U.S. for campus life and career opportunities.

Iowa State University is a welcoming, global, and culturally diverse community of students, faculty, and staff. Campus community members have a wide range of backgrounds and experiences and are committed to engaging with each other respectfully as outlined in the university's Principles of Community (https://www.iastate.edu/diversity-and-inclusion/principles-community) . Iowa State recognizes that diverse intellectual and philosophical perspectives are vital to innovation, critical thinking skills, and a dynamic academic community that fosters the land-grant ideals of putting science, technology, and human creativity to work.

All offers of employment, oral and written, are contingent upon the university’s verification of credentials and other information required by federal and state law, ISU policies/procedures, and may include the completion of a background check and/or a consumer credit check.

Iowa State University is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, genetic information, national origin, marital status, disability, or protected veteran status and will not be discriminated against. Inquiries can be directed to the Office of Equal Opportunity, 3410 Beardshear Hall, 515 Morrill Road, 515 294-7612, email eooffice@iastate.edu .

If you have questions about the application process please email employment@iastate.edu or call 515-294-4800 or Toll-Free at 1-877-477-7485 . Iowa State University provides reasonable accommodations to applicants and employees with disabilities. Applicants with questions about access or requiring a reasonable accommodation for any part of the application or hiring process should email employment@iastate.edu or call (515) 294-4800 or Toll-Free: (877) 477-7485 . TTY users are welcome to use the Iowa Relay Service number by dialing 7-1-1 or (800) 735-2942 .

General ISU compensation information can be found on the University Human Resources (https://www.hr.iastate.edu/careers/compensation) website. Please note that this is only a list of ranges and individuals will be paid commensurate with qualifications.